i-On By Dr. Xi

health AI/medtech skincare research (clinical science-backed skincare)

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StageNo funding raised

Raised$0

Founded2021

Employees3

LocationNew York, NY

Business modelB2C / D2C skincare brand (retail products)

Valuation$1,100,000

About

Founded by Dr. Xi Huang, one of the world’s leading experts on the correlation between high iron levels and health, i-On® Skincare is a groundbreaking beauty brand featuring patented Age Disrupting DII® Technology – a breakthrough solution to the impact of excess iron on the surface of the skin backed by 30 years of research. After finding excess iron to be the element most responsible for the appearance of skin aging, Dr. Huang founded Fe:I Beauty Tech and developed the cornerstone of i-On Age Disrupting Skincare: De-Ironizing Inducer (DII®) Technology. DII® is an unprecedented synergy of active ingredients that does what no other cosmetic product can do. It exfoliates excess iron from the surface of the skin to help inhibit the formation of the free radicals that cause the visible signs of skin aging – effectively disrupting and defying the aging process. Launched in 2021, i-On is available at ionskincare.com DTC and Nordstrom.com.

Product

Value proposition: Anti-aging skincare designed to address excess iron in the skin, with clinical evidence and science-driven formulations that reduce redness, wrinkles, and age spots
Target customers: individual consumers seeking anti-aging skincare, professional clinics/spas

Founders

Xi Huang — Founder and President

Products

Age Disrupting Skin SerumEye CreamDiscovery Age Disrupting Skin Cream 10mlDiscovery Age Disrupting Eye Cream 5mlLuxurious skincare productsIron Rebalancing Capsule Starter 30 capsulesBest Eye Cream

Key features

reduces visible rednessreduces wrinkles and fine linesfirmer, more resilient skinbrighter and even tonereduces appearance of age spotsremoval of excess iron from skin surfacesunscreen protection support from withingentler than retinols and exfoliating acidsclinical studies showing 100% participants improved

Technologies

DII technologyiron-focused skincare scienceclinical testingtoxicity/pharmacology research

Target conditions

aging skinrednessfine lines/wrinklesage spotsdiscoloration

Care settings

homeclinic/med spa (used in leading med spas and dermatology offices)professional treatment regimes

Certifications

HIPAA?CLIA?SOC 2?HITRUST?

Notable customers

Leading Med Spas and Dermatology Offices (mentioned)

Partnerships

none specified

Awards

none specified

Traction metrics

clinical study results: 100% positive improvements

News

i-On By Dr. Xi Announces Peer-Reviewed Study Linking Excess Iron to Visible Skin Aging and Inspiring Next-Generation Skincare PRUN · 2025-06-27T17:36:11.000Z
Maximizing Efficiency: How i-On by Dr. Xi Might Be the Key to Your Health Success | Wellness Master Club · 2025-06-04T08:14:37.000Z
Unlocking Lacrimal Gland Potential: i-Onion™’s Novel Approach to better | ESCRS iNovation® Day 2025 · 2025-11-28T14:48:33.000Z
Evaro raises $25M to bring NHS healthcare straight into your favourite consumer apps — TFN · 2026-01-27T08:29:20.000Z
Mapping AI startup investment and innovation in healthcare using a ... · 2026-04-14T00:00:00.000Z
iCarbonX interview: How AI could predict your health from one drop of blood · 2025-08-18T09:31:27.000Z

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Profile updated Jul 29, 2026. Sources: ionskincare.com