Metabolic Solutions Development Company (United States)

drug discovery and development company investigating new molecular targets and developing novel therapeutics to treat metabolic diseases

health AI? (not explicitly stated) | metabolic diseases; biotech/pharmaceutical R&D

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StageSeries B

Raised$58.5M

Founded2006

Employees3

LocationKalamazoo, MI

Business modelB2B/B2C? (not clearly stated) SaaS not applicable; null

About

Metabolic Solutions Development Company (MSDC) is a drug discovery and development company investigating new molecular targets and developing novel therapeutics to treat metabolic diseases associated with age-related mitochondrial dysfunction, especially insulin resistance and type 2 diabetes. The company's pipeline includes MSDC-0160 and CIRIUS MSDC-0602, insulin sensitizer programs targeting metabolic syndrome, type 2 diabetes, and neurodegeneration.

Product

Value proposition: Developing novel therapeutics to address metabolic diseases tied to age-related mitochondrial dysfunction, with a focus on insulin resistance and type 2 diabetes

Founders

Jerry Colca — Co-founder
Rolf Kletzien — Co-founder

Products

MSDC-0602KCirius Therapeutics collaboration (contextual)MSDC-0160CIRIUS-MSDC-0602 platforminsulin sensitizers (programs)

Key features

Targeted metabolic disease therapeuticsdrug discovery and developmentnovel molecular targetsclinical program pathways (e.g., MSDC-0602K)

Technologies

Mitochondrial dysfunction targetinginsulin sensitizersdrug discovery platformstarget discoverypreclinical/clinical development

Target conditions

Type 2 diabetesinsulin resistancemetabolic syndromeage-related mitochondrial dysfunctionNASH (as context from MSDC-0602K program)

Partnerships

Cirius Therapeutics collaborationFrazier Healthcare Partners and Novo A/S (investors)

Investors

Hopen Life SciencesSouthwest Michigan First Life Science Fund

News

Company - GT Metabolic Solutions · 2024-07-17T19:49:22.000Z
Melyssa Wagner · 2026-06-11T22:26:41.000Z
GT Metabolic Solutions - 2026 Company Profile, Team, Funding & Competitors - Tracxn · 2023-06-26T12:17:56.000Z
GT Metabolic™ Solutions, Inc., opens doors to new surgical platform as FDA grants De Novo marketing authorization to its novel magnet compression anastomosis technology · 2024-09-04T14:00:00.000Z
Startup Nula Emerges to Advance a New Class of Medicines for Metabolic Disease - MedCity News · 2026-04-16T19:15:21.000Z
Danforth Technology Company Launches New Startup Metablify - Danforth Technology Company · 2024-10-28T13:00:54.000Z

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Profile updated Jul 29, 2026. Sources: msdrx.com