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U.S. Healthcare Startup Index

biotech startups

A live directory of U.S. healthcare startups. Filter by state and vertical to see stage, funding, founders, and what each company ships.

Healthcare AI index

Showing 11–20 of 28 startups

Helicore Biopharma

Long-Acting Medicines to Transform Metabolic Health

San Mateo, CAFounded 20256 employees

Helicore Bio is developing long-acting therapies in obesity and cardiometabolic disease using our proprietary antibody-peptide conjugate platform. We have developed proprietary libraries of GLP-1R agonist and amylin rec…

biotechhealth AImedtech (metabolic diseaseSeries ARaised $65M

ImYoo

Patient-driven biodiscovery platform advancing immune biology with patients at the center

Mountain View, CAFounded 20218 employees

ImYoo is debugging the human immune system. By coupling at-home blood collection and single-cell RNA sequencing, we enable high resolution insights across time.

health AI / medtech / digital healthseed

B2B2C / platform

ImmunoMetabolix

Unlocking The Power Of Metabolically-Fit Immune Cells

Bridgewater, NJ3 employees

Is a clinical-stage biotechnology company focused on applying a novel engineering approach to develop metabolically-fit immunotherapies for patients with cancer, autoimmune, and inflammatory diseases.

health AI / medtech / digital health
Boston, MAFounded 202211 employees

Today, the biggest bottleneck in genetic medicine isn’t the power of mRNA, CRISPR, or gene therapy—it’s that we can’t get these medicines anywhere but the liver. Our RAPTOR™ platform is the first AI-driven system that m…

health AI/biotechgene therapygenetic medicinesSeedRaised $31M

not explicitly stated

Metanoia Bio Inc.

Revolutionary Regenerative Medicine

los angeles, CAFounded 20204 employees

Metanoia: Where Regeneration Takes Center Stage At Metanoia, we're rewriting the future of healthcare. We're pioneering a revolutionary approach to regenerative medicine that targets the root cause of chronic and age-re…

health AI/biotech regenerative medicineDebt, Option to AcquireRaised $1,195,257
Cambridge, MAFounded 20244 employees

Determining treatment effectiveness, discovering new biology using AI enabled nanosensor technology. A faster path to the most effective treatment with better outcomes. We develop holistic profiles based on a patient's…

health AImedtechprecision medicinePre-seedRaised $250,000

Oral Genome

Decode Your Saliva™

Carlsbad, CAFounded 20217 employees

Oral Genome is a saliva-based screening platform based in Carlsbad, California that delivers oral and whole-body health risk insights in under 2 minutes using point-of-care testing. The platform uses a collection sponge…

health AImedtechdigital healthSeed VCRaised $3.12M - $3.23M

B2B/B2C SaaS (provider portals, clinical tools, individual insights)

Phinomics

From Invisible Biology to Tomorrow’s Therapeutics

San Carlos, CA9 employees

Phinomics is unlocking a hidden layer of biology—circular DNA and cryptic proteins—to power the next generation of AI in precision medicine. While others models train on a static, 1-D linear genome, we see a 3D, dynamic…

health AI / biotech / medtechSeed / Incubator/Accelerator

Response Pharmaceuticals

Targeted Solutions for Weight Management and Metabolic Health

Mclean, VAFounded 20224 employees

Response Pharmaceuticals is developing its lead asset, RDX-002, a first-in-class weight management and cardiometabolic health drug with confirmed efficacy and safety in >550 subjects. All programs are in Phase 2 clinica…

health AI/biotech? (note: primarily biotech/medtech focused on weight management and metabolic health)Series ARaised $7.99M - $8M
Cambridge, MAFounded 20243 employees

Riboway Therapeutics is a Boston-based biotech leveraging AI to decode RNA biology and develop RNA-targeted therapeutics. We aim to revolutionize how targets are drugged and make every protein druggable. Our smart RNA-t…

health AIbiotechmedtechunfundedRaised $0
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