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U.S. Healthcare Startup Index

biotech startups

A live directory of U.S. healthcare startups. Filter by state and vertical to see stage, funding, founders, and what each company ships.

Healthcare AI index

Showing 1–10 of 28 startups

Acrobat Genomics

Designing the future of programmable biology

San Carlos, CAFounded 20225 employees

Acrobat Genomics builds AI-driven protein and genome engineering platforms for pharma, biotech, and research institutions. The company's AcrobaTx Engine is a closed-loop system that uses AI to propose therapeutic candid…

health AImedtechbiotechSeed / Grant-backed

B2B, likely SaaS/platform with collaborations

San Diego, CA2 employees

AivoCode is a neuroscience-focused biotech startup that is pioneering the development of innovative and broad platform technologies to improve the treatment and management of neurological diseases such as brain injury,…

biotechhealth AIneurodegenerative diseasesSeedRaised $5.6M

B2B, B2B2C, research collaborations (inferred via startup biotech model)

La Jolla, CA11 employees

We now know that immune cells – not only in the body’s periphery but especially in the brain – can produce autoantibodies that cause severe neurological and psychiatric diseases. Founded to explore the latest discoverie…

health AI? or neuroimmunology-based precision medicines for autoimmune neuropsychiatric disease (neuropsychiatric autoimmune)SeedRaised $58M
Watertown, CTFounded 20242 employees

Blissgene Therapeutics is a pioneering biotech startup on a bold mission to redefine the treatment of chronic pain, anxiety, and depression. We are on a quest of building gene therapies designed to address the root caus…

biotech / health AI / medtech (gene therapy)early stage, actively fundraisingRaised $5,000
Pittsburgh, PAFounded 20204 employees

Duo Oncology, founded by oncologists, is developing tumor-penetrating nanomedicines to upgraded the foundations of cancer medicine. Duo’s patented platform prodrug chemistry releases creates nanomedicines that penetrate…

health AI? medtech? oncology drug development (biotech)SeedRaised $6.8M

Entirety Biomedical

High Performance Absorbable Metal Implants

NewarkFounded 20223 employees

Entirety Biomedical is working to become the standard of care in ortho fixation implants, starting with maxillofacial and extremities, to offer cosmetic trauma and reconstruction surgery patients pain-free restoration o…

medtech / health AI?SeedRaised $1.23 million

Episteme Prognostics, Inc.

Transforming Cancer Therapy with Precision Epigenetics

Brooklyn, NY3 employees

Episteme Prognostics is a precision medicine company pioneering epigenetic diagnostics to transform how cancer therapy is selected and delivered. Our mission is to help oncologists identify which patients will truly ben…

health AI/biotechEarly Stage VC / Series ARaised $6.61M

Exactics, Inc.

Building The Future of At-Home Diagnostics

Chicago, ILFounded 20219 employees

Exactics is a biotech startup committed to developing rapid, reliable, and cost-effective at-home diagnostic technologies for infectious diseases. Our flagship product is TiCK Test, the first ever fully at-home screenin…

health AI / digital health / at-home diagnosticsseedRaised $1.5 million

GNOMX Corp.

Next-generation epigenetic / AI diagnostic platform for infectious disease

New York, NYFounded 20222 employees

GNOMX was founded to commercialize host response epigenetic diagnostics based on research funded by a $46 million DARPA ECHO contract to an academic consortium led by the Icahn School of Medicine at Mount Sinai, Yale Un…

health AIdiagnosticsinfectious diseaseSpin-off, BARDA-funded contract recipientRaised $749,700

Gordion Bioscience

Gordon Bioscience

Boston, MAFounded 20236 employees

Gordion Bioscience has built a proprietary patient-derived dependency map across 20,000 genes and 26 cancer types - translating real tumor biology into pipeline decisions.Standard preclinical models (CRISPR screens, cel…

biotech / health AI / medtech (cancer therapeutics)SeedRaised $120K
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