About
3Daughters is a clinical development company focused on Evolutionary Healthcare for Women. Our first evolution is a frameless, magnetic, nonhormonal intrauterine device (IUD) based on physics and geometry for long-acting contraception. Our unique IUD was designed to improve upon the outdated T-shape frame of current IUDs that causes pain, perforation and expulsion. These problems lead to a ‘fear factor’ for women and practitioners inserting the device. Current IUDs also require dangling strings for retrieval- a nuisance factor for women and their partners. 3Daughters newly designed IUD conforms naturally to a woman’s body and will address the 'fear factor', pain and other problems of current IUDs …with no strings attached! Nearly all women use contraception in their lifetimes, and we plan to make it better.
Product
- Value proposition
- Transforming women’s healthcare with a novel, integrated uterine drug delivery IUD system that is frameless, non-hormonal, and designed for a better IUD experience.
- Regulatory
- preclinical development; plans to file IND and begin Phase 1 in 2025
Founders
- Mary Beth Cicero (CEO) — Co-Founder and CEO
- Shelley Amster (CBO) — Co-Founder and Chief Business Officer (also referred to as Chief Strategy & Growth Officer)
- Carlos Gradil (Inventor) — Inventor and Professor of Veterinary & Animal Science, Equine Studies, UMass Amherst
Categories
Products
Key features
Technologies
Target conditions
Care settings
Traction metrics
Investors
News
- 3Daughters Announces NIH to Support Testing of Novel Frameless Magnetic Copper IUD (3D-001) for Contraception - 3Daughters · 2024-09-25T07:00:13.000Z
- 3Daughters closes oversubscribed $4.7m seed funding for novel IUD contraception · 2024-07-19T19:32:00.000Z
- 3Daughters to Lead Panel at BIO International Convention on Patient Reported Outcomes that Includes FDA Division Director - 3Daughters · 2025-06-16T09:00:54.000Z
- 3Daughters Selects Connect Labs by Wexford - Baltimore for New Corporate Headquarters - 3Daughters · 2025-05-14T09:00:53.000Z
- Breakthrough IUD Faces Familiar Funding Barrier in Women’s Health · 2025-07-08T04:00:00.000Z
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Profile updated Jul 29, 2026. Sources: 3daughtershealth.com


