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U.S. Healthcare Startup Index

MedTech startups

A live directory of U.S. healthcare startups. Filter by state and vertical to see stage, funding, founders, and what each company ships.

Healthcare AI index

Showing 11–19 of 19 startups

Medsense Health

Operational infrastructure for pharmacy clinical services

Madison, WIFounded 201911 employees

Medsense Health is the operational infrastructure layer powering modern pharmacy clinical services. We help pharmacies launch, operate, and scale reimbursable adherence and monitoring programs — combining technology, pa…

health AI/clinical operations for pharmacyUnattributed VCRaised $9.47M

B2B, SaaS plus services (operational as a service)

Melorix Medical™

Transforming small vessel anastomosis for better health

Boston, MAFounded 20252 employees

At Melorix Medical, Inc., our mission is to revolutionize the field of small vessel anastomosis. Through technologies such as our patented LymphoLock, we are dedicated to developing innovative devices that enhance the s…

health AI/medtech startup focused on lymphatic surgery devicesnot applicable (participated in Purdue Innovates Firestarter Program and MESH Core Healthcare Innovation Bootcamp)Raised $0

B2B (medical device development and potential collaboration with surgeons/clinics)

Metfora Diagnostics

Detect disease earlier with a single blood test

Tucson, AZFounded 20205 employees

THE PROBLEM 45% of Americans suffer from at least one chronic disease. The biological processes of chronic diseases, however, progresses over decades. In fact, patients presenting common symptoms of fatigue or dizziness…

health AI / medtech / digital healthPre-Clinical TrialsNot YC-backed, but has participated in various accelerator/incubator programsRaised $131K to $285K

B2B / B2B2C (providers and healthcare systems)

OnPoint Vision, Inc.

Developing intraocular lenses to correct residual refractive error after cataract surgery and treat age-related retinal pathologies

Aliso Viejo, CAFounded 20197 employees

Our mission is to provide a highly differentiated minimally-invasive surgical solution designed to customize the visual outcome of the pseudophakic eye. Primary product is the AccuraSee Intraocular Pseudophakic Contact…

healthcare AI/medtech ophthalmologySeries BRaised $11 million

B2B, likely SaaS/product

Phenomix Sciences

AI driven precision obesity medicine

Saint Paul, MNFounded 202114 employees

Phenomix Sciences is a precision medicine obesity biotechnology pioneer on a mission to conquer obesity globally through the science of phenotyping, the understanding of how genes combined with environmental and behavio…

health AIprecision medicineobesity/metabolic healthSeries A2Not YC-backedRaised $14.25M

B2B, SaaS

San Francisco, CAFounded 20238 employees

🎯 Our Mission: At PhyxUp Health, we are committed to helping physical therapy practices overcome the limitations of traditional in-person care. By leveraging digital health solutions like Remote Therapeutic Monitoring…

health AItelehealthphysical therapySeed

B2B SaaS with managed services

Saint Paul, MNFounded 20255 employees

Healthcare systems are operating under sustained workforce and financial pressure. Nursing shortages, rising labor costs, and growing accountability for outcomes are forcing providers to manage higher acuity patients wi…

health AI / medtech / digital healthRaised $200,000

SynchNeuro, Inc.

The world’s first non-invasive, brain-based continuous glucose monitor.

Chicago, ILFounded 20219 employees

At SynchNeuro, we are transforming how people monitor and manage their health with the world’s first non-invasive brain-based continuous glucose monitor. Our sensor, discreetly worn behind the ear, analyzes brain signal…

health AImedtechwearablesSeedRaised $3 million

B2B2C, partnerships with investors and accelerators (implicit)

irvine, CA18 employees

We make a wearable device that monitors blood pressure continuously. We're on a mission to save lives through providing patients and providers better data and more actionable insights.

health AI / medtech / digital health (cardiovascular monitoring)Seed, YC-backedY CombinatorRaised $1.43M
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