Stageunfunded
Raised$0
Founded2022
Employees2
LocationBoston, MA
Valuation$1,100,000
About
Neoclease is a biotechnology company pioneering AI-designed gene-editing therapies optimized for individual genes. Using a proprietary platform that integrates generative protein models with synthetic biology, Neoclease builds ultra-precise, delivery-ready nucleases for diseases with high unmet need. Its lead program targets LRRK2 to halt progression of Parkinson’s disease. Neoclease’s approach enables the development of editors with enhanced specificity, efficiency, and size, unlocking new possibilities across thousands of genetic diseases.
Product
- Value proposition
- Precision Gene Editing with AI to design custom nucleases for targeted gene therapies, aiming to improve lives and accelerate advancement in gene editing
Founders
- Chelsea Trengrove — CEO and Cofounder
- Jin Liu — CTO and Cofounder
- Vivek Gowda — Co-Founder
Categories
BiotechGenomicsAI in Healthcare
Products
custom nucleasesGenAI-designed gene-editing enzymes
Key features
GenAI model to design miniaturized, precise, and efficient nucleasesTargeted gene editing for therapeutic editing in challenging tissuesaim to reduce side effects and enable precision medicinecollaboration with industry leaders to drive innovation
Technologies
Generative AISynthetic biologyNuclease designgene editingtherapeutic editing
Target conditions
Parkinson’s diseasegenetic disordersgene-editing therapies
Partnerships
collaborations with industry leaders to drive innovation in gene editing technologies and therapies
News
- MilliporeSigma Announces Neoclease as Winner of 2025 NorthAmerican Advance Biotech Grant · 2025-06-19T05:26:52.000Z
- MilliporeSigma Announces Neoclease as Winner of 2025 North American Advance Biotech Grant · 2025-06-18T08:07:29.000Z
- MilliporeSigma Announces Neoclease as Winner of 2025 North American Advance Biotech Grant · 2025-06-18T00:00:00.000Z
- MilliporeSigma Announces Neoclease as Winner of 2025 North American Advance Biotech Grant · 2025-06-18T12:00:00.000Z
- Neoclease Awarded Yearlong Residency at The Engine Following AgingCode Summit · 2025-06-14T05:20:23.000Z
- Neoclease Joins the LabCentral AI BioHub in Partnership with C10 · 2025-07-01T07:00:00.000Z
Browse similar startups
Related startups
- Neuronity — Mansfield, MA
- Nine Diagnostics — Cambridge, MA
- Novastra Therapeutics — Boston, MA
- NxtCure — Boston, MA
- OncoSys AI — Cambridge, MA
- Onduo by Verily — Newton, MA
- Nephrology Specialists PC - Richmond VA — Mechanicsville, VA
- Nest Genomics (YC W22) — New York City, NY
- Nest Health — New Orleans, LA
- NeuraEase — Poughkeepsie, PA
- Neural Wave Inc. — atlanta, GA
- NEVADA CARDIOLOGY ASSOCIATES — Las Vegas, NV
Profile updated Jul 29, 2026. Sources: neoclease.ai
