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Stipple Bio

health AI / medtech / biotech
StageSeries A
Raised$109 million
Founded2022
Employees13
LocationCambridge, MA

About

Stipple Bio is a biotechnology company harnessing epitope-level precision to create targeted cancer therapies through our proprietary Pointillist Platform, which is designed to identify tumor-specific cell surface epitopes with greater precision. By enabling more selective targeting of cancer cells, the platform aims to improve therapeutic index and unlock targets that have been difficult to address using conventional oncology drug discovery methods. We’re advancing our lead candidate ADC STP-100 as an early application of our epitope-targeting approach. Founded in 2022 by cancer biology pioneers Aaron Ring (Fred Hutchinson Cancer Center) and Aashish Manglik (University of California, San Francisco), Stipple Bio is grounded in deep expertise across cancer biology, chemical biology and translational science. Our financing was co-led by RA Capital, a16z Bio+Health and Nextech Invest, and includes participation from existing investors Emerson Collective Investments (managed by Yosemite), GV (Google Ventures), LoLa Capital Partners and GordonMD Global Investments, among others. Stipple Bio is building a pipeline of next-generation oncology therapeutics with the goal of developing life-changing medicines for cancer patients.

Product

Value proposition
Revolutionizing targeted oncology with epitope-level precision to develop life-changing medicines for people with cancer.
Target customers
biotech and pharmaceutical companies

Founders

  • Aaron Ring
  • Aashish Manglik

Categories

biotechoncologyepitope mappingantibody discovery

Products

Platform for epitope-level discovery and antibody development

Key features

epitope-level precisiontumor-specific epitopes mappingstipple/dot-based discovery approachtarget discovery across established, emerging, and novel targets

Technologies

epitope mappingepitope-level precisionpointillism/stippling approachantibody discovery

Integrations

EHRs / platforms / systems it integrates

Target conditions

cancer

Investors

RA Capital ManagementAndreessen Horowitz (a16z Bio+Health)Nextech InvestEmerson Collective Investments (managed by Yosemite)GV (Google Ventures)LoLa Capital PartnersGordonMD Global InvestmentsOMX

News

More links

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Profile updated Jul 29, 2026. Sources: stipple.bio, linkedin.com

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