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U.S. Healthcare Startup Index

The intelligence layer for clinical AI.

A live directory of U.S. healthcare startups. Filter by state and vertical to see stage, funding, founders, and what each company ships.

Healthcare AI index

Showing 691–700 of 1,006 startups

Pleural Dynamics, Inc.

First-of-its-kind ACES implant to treat recurrent pleural effusions

Wayzata, MNFounded 20205 employees

Pleural Dynamics is a Minneapolis based medical device start-up focused on developing best in class solutions for chronic, recurrent fluid collections within the body. Our flagship product, ACES (the Automatic Continuou…

health AI/medtech startup focused on pleural effusion managementLater Stage VCRaised $8.28M

B2B/B2C SaaS? (device implant with reimbursement coding)

Plexis.ai (Techstars '25)

The Execution Layer for Healthcare AI

Delaware, DEFounded 20253 employees

Orchestrate physician-workflows across systems and EHRs under a secure, auditable infrastructure. Built for healthcare innovation — enabling secure data exchange, real-time automation, and adaptive AI integration.

health AIhealthcare IThealthtechTechstars-backedTechstars Tokyo 2025Raised $220.0K

B2B, SaaS

Plinth Analytics

Elevate Your Data

New York, NY3 employees

Plinth is a boutique data analytics services and consulting company founded in 2022. Our mission is to enable decision-makers to obtain meaningful, robust, and repeatable insights from real-world data.

health AI / real-world data / healthcare analyticsNot publicly disclosed/UnknownNot publicly disclosed/UnknownRaised Not publicly disclosed/Unknown

SaaS / services (code-first solutions)

The Woodlands, TXFounded 20153 employees

Clinical informatics consulting firm that helps health care organizations and physicians realize the value proposition of electronic health records (EHRs). Specializing in Epic. Services for Health Care Organizations: •…

Series A - IIRaised $25.78M

PointHealth AI

Optimizing prescriptions with AI

San Francisco, CA7 employees

At PointHealth, we believe no one should endure the pain of trial-and-error healthcare. We envision a future of medicine where prescribers have the exact tools they need to provide their patients the best possible outco…

health AIdigital healthprecision medicineVC-backed; actively seeking Series A

B2B2C, SaaS

Boston, MAFounded 20155 employees

ChroniSense Medical is now Polso! We’ve changed our name to better align with our novel solution. Follow us here or visit us at polsohealth.com to stay up-to-date on all things Polso. Polso is a digital health company t…

Medtechhealth AIremote patient monitoringSeed, Pre-SeedPlug and Play (Incubator/Accelerator)Raised $1M

Polygon Health Analytics LLC

Polygon Health Analytics | Real-World Data | AI-Driven Healthcare Insights

Philadelphia10 employees

Founded in January 2023 by the highly cited data scientist in healthcare, Dr. Lixia Yao, Polygon Health Analytics LLC may be a young company, but our team is composed of experts with decades of experience and a deep und…

health AIreal-world datahealth economics and outcomes research (HEOR)Government grant funded (SBIR)Raised $695,909

Pops

Best Diabetes Management App | Care | Pops

Oak Park Heights, MNFounded 20134 employees

Pops offers a consumer-centric solution for self-management of diabetes. Pops is centered around a personalized app-based AI virtual coach that is paired with an easy to use, discreet, smart-glucose meter. This provides…

health AIdigital healthmedtechSeries ARaised $10.2M

B2B2C / B2C SaaS with hardware integration

Atlanta, GAFounded 20172 employees

The mission of Postpartum Support International, Georgia Chapter (PSI GA) is to promote awareness, prevention, and treatment of maternal mental health issues related to childbearing in Georgia. Our goal is for every wom…

mental health / perinatal mental healthNon-profit organization (not a startup)Raised Not specified (non-profit funded through grants, donations, and contracts)

nonprofit / nonprofit fundraising and programs

Prairie Oral Surgery Ltd

Prairie Oral & Facial Surgery | Fargo Oral Care

Fargo, ND5 employees

Prairie Oral & Facial Surgery in Fargo, North Dakota offers comprehensive oral and facial surgery services including dental implants, wisdom tooth removal, tooth extractions, bone grafting, and pediatric oral surgery. T…

oral surgerydental implantsfacial reconstructionPrivate company; no evidence of venture capital funding rounds found.Not applicable (not a venture-backed startup)Raised Not applicable (not a venture-backed startup)
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